Passiflora incarnata Linn: A phytopharmacological review

Authors

  • S. S. Patel
  • T. S. Mohamed Saleem
  • V. Ravi
  • B. Shrestha
  • N. K. Verma
  • K. Gauthaman

DOI:

https://doi.org/10.22377/ijgp.v3i4.100

Abstract

Medicinal plants are the nature’s gift to human being to have disease-free healthy life. It plays a vital role to preserve our health. India is one of the most medico-culturally diverse countries in the world where the medicinal plant sector is part of a time-honoured tradition that is respected even today. Medicinal plants are believed to be much safer and proved elixir in the treatment of various ailments.  In our country, more than 2000 medicinal plants have been recognized. Passiflora incarnata (Passifloraceae; passion flower Family) is an important medicinal plant of tropical and subtropical India. Its medicinal usage has been reported in the traditional systems of medicine such as Ayurveda, Siddha and Unani. P. incarnata has been described as a passion flower and has been used extensively for
treatment of some diseases like as anxiety, insomnia, convulsion, sexual dysfunction, cough and cancer. The present article including the detailed exploration of phyto-pharmacological properties of P. incarnata is an attempt to provide a direction for further research.
Key words: Anti-cancer, anxiety, aphrodisiac, Passiflora incarnata

Downloads

Download data is not yet available.

References

Kinghorn GR. Passion, stigma, and STI. Sex Transm Inf

;77:370‑5.

Dhawan K, Dhawan S, Sharma A. Passiflora: A review update.

J Ethnopharmacol 2004;94:1-23.

Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A,

Rashidi H, Khani M. Passionflower in the treatment of generalized

anxiety: A pilot double-blind randomized controlled trial with

oxazepam. J Clin Pharm Ther 2001;26:363-7.

Reginatto FH, de-Paris F, Petry RD, Quevedo J, Ortega GG,

Gosmann G, et al. Evaluation of anxiolytic activity of spray dried

powders of two South Brazilian Passiflora species. Phytother Res

;20:348-51.

Wheatley D. Medicinal plants for insomnia: A review of their

pharmacology, efficacy and tolerability. J Psychopharmacol

;19:414-21.

Akhondzadeh S, Kashani L, Mobaseri M, Hosseini SH, Nikzad S,

Khani M. Passion flower in the treatment of opiates withdrawal:

A double-blind randomized controlled trial. J Clin Pharm Ther

;26:369-73.

Ichimura T, Yamanaka A, Ichiba T, Toyokawa T, Kamada Y,

Tamamura T, et al. Antihypertensive effect of an extract of Passiflora

edulis rind in spontaneously hypertensive rats. Biosci Biotechnol

Biochem 2006;70:718-21.

Rowe CA, Nantz MP, Deniera C, Green K, Talcott ST, Percival SS.

Inhibition of neoplastic transformation of benzo [alpha]

pyrene‑treated BALB/c 3T3 murine cells by a phytochemical extract

of passion fruit juice. J Med Food 2004;7:402-7.

Nassiri-Asl M, Shariati-Rad F, Zamansoltani F. Anticonvulsant

effects of arial parts of Passiflora incarnata extract in mice:

Involvement of benzodiazepine and opioid receptors. BMC

Complement Altern Med 2007;7:26.

The Wealth of India. A Dictionary of Indian Raw Materials and

Industrial Products. CSIR;7:278-9.

Dhawan K, Sharma A. Restoration of chronic- D9-THC-induced

decline in sexuality in male rats by a novel benzoflavone moiety

from Passiflora incarnata Linn. Br J Pharmacol 2003;138:117-20.

Dhawan K, Kumar S, Sharma A. Reversal of cannabinoids (delta

‑THC) by the benzoflavone moiety from methanol extract of

Passiflora incarnata Linn in mice: A possible therapy for cannabinoid

addiction. J Pharm Pharmacol 2002;54:875-81.

Strohalm H, Dregus M, Wahl A, Engel KH. Enantioselective

analysis of secondary alcohols and their esters in purple and yellow

passion fruits. J Agric Food Chem 2007;55:10339-44.

Dhawan K, Kumar S, Sharma A. Nicotine reversal effects of the

benzoflavone moiety from Passiflora incarnata Linn in mice. Addict

Biol 2002;7:435-41.

Dhawan K, Kumar S, Sharma A. Suppression of alcohol‑cessationoriented

hyper-anxiety by the benzoflavone moiety of Passiflora

incarnata Linn. in mice. J Ethnopharmacol 2002;81:239-44.

Miyasaka LS, Atallah AN, Soares BG. Passiflora for anxiety

disorder. Cochrane Database Syst Rev 2007;24:CD004518.

Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on

extracts of Passiflora incarnata Linneaus. J Ethnopharmacol

;78:165‑70.

Brown E, Hurd NS, McCall S, Ceremuga TE. Evaluation of the

anxiolytic effects of chrysin: A Passiflora incarnata extract, in the

laboratory rat. AANA J 2007;75:333-7.

Chen S, Kao YC, Laughton CA. Binding characteristics of

aromatase inhibitors and phytoestrogens to human aromatase.

J Steroid Biochem Mole Biol 1997;61:107-15.

Dhawan K, Sharma A. Prevention of chronic alcohol and

nicotine‑induced azospermia, sterility and decreased libido, by a

novel tri-substituted benzoflavone moiety from Passiflora incarnata

Linn. in healthy male rats. Life Sci 2002;71:3059-69.

Dhawan K, Kumar S, Sharma A. Aphrodisiac activity of methanol

extract of leaves of Passiflora incarnata Linn in mice. Phytother Res

;17:401-3.

Dhawan K, Kumar S, Sharma A. Antiasthmatic activity of the

methanol extract of leaves of Passiflora incarnata. Phytother Res

;17:821-2.

Dhawan K, Kumar S, Sharma A. Antitussive activity of the

methanol extract of Passiflora incarnata leaves. Fitoterapia

;73:397-9.

Beaumont DM. The effects of chrysin: A Passiflora incarnata

extract, on natural killer cell activity in male Sprague-Dawley rats

undergoing abdominal surgery. AANA J 2008;76:113-7.

Benson VL, Khachigian LM, Lowe HC. DNAzymes and

cardiovascular disease. Br J Pharmacol 2008;154:741-8.

Downloads

Issue

Section

Articles