Phytochemical and antioxidant evaluation of Ipomoea reniformis

Abstract

Objective: Ipomoea reniformis was studied for its traditionally claimed activity, and still, it is unexplored. The plant can be further explored for the study of traditionally claimed unexplored activities, as well as isolation and identification of active constituents may lead to new findings. The objective of our study is to investigate antioxidant activity of the extracts of I. reniformis using in vitro models. The measured quantity of extract of I. reniformis was evaluated for its antioxidant activity as compared with standard by different models. The present investigation may be concluded that the plant I. reniformis is endowed with significantly antioxidant activity due to the presence of phenolics and flavonoids, thereby justifying its use in the indigenous system of medicine. Materials and Methods: I. reniformis was collected, dried, and extracted with different solvents, and finally, five extracts were studied for their total phenolics and flavonoids content followed by determination of antioxidant activity by 1, 1-diphenyl-2-picrylhydrazyl, superoxide radical scavenging, and α-amylase inhibitory activity. Results: The obtained results showed that ethanolic extract contains a higher concentration of phenolics and flavonoids and showed highest antioxidant activity among all the samples. Conclusion: The plant showed the antioxidant activity, and we believe that antioxidant activity of I. reniformis was due to synergistic effect of phytochemicals present in it. Further evidencing the need to conduct studies that can identify the active components responsible for the activity.