Genetic association of infertility in vataj prakriti female patients with reproductive age group

Abstract

Background: According to the ancient system of medicine Vataj Prakriti females are more prone for infertility. Many studies have been carried out to determine the association between Dehaj Prakriti and specific diseases, whereas to understand the direct relationship between Vataj Prakriti and infertility still need more studies. Objective: The objective of the study was to investigate the association between infertility and Prakriti using modern diagnostic tool, i.e., Karyotyping. Materials and Methods: This study was conducted as a randomized controlled study on 50 infertile females by evaluating their Prakriti and Karyotyping and to find out the relationship between both of them. Study was conducted at Sir Sunderlal Hospital, IMS, BHU, and Cytogenetic Lab, Department of Anatomy, IMS, BHU. Prakriti was assessed by Performa (questionnaire-based) and Karyotyping was done by G-banding Technique. Correlation between Prakriti and Karyogram and other factors such as age, chief complaints, menstrual history, and endocrine profile were assessed. Results: The overall Vataj Prakriti females were 72% out of these 01% are Turner’s, and 18% are Turner Mosaic. The study identified a statistically significant relationship between Vataj Prakriti and infertility. Conclusion: Results of the present study suggested that the Vataj Prakriti females were more prone for infertility than pittaj and kaphaj Prakriti and all abnormal karyogram is also associated with Vataj Prakriti.