Effect of analgesic activity in crude extract and isolated compounds of Tecomaria capensis

Abstract

Aim: The leaves of the plant Tecomaria capensis were extracted with different solvents and screened for their analgesic activity. Materials and Methods: The ethyl acetate extract of the plant T. capensis has showed the presence of flavonoids, glycosides, steroids, and terpenoids. The analgesic activity of ethyl acetate extract of T. capensis leaves is evaluated by Eddy’s hot plate and tail flick method. Results and Discussion: This study demonstrates that ethyl acetate extracts of T. capensis have significant analgesic activities. Further, with column chromatography technique, different compounds are isolated from the extract. Among the different compounds, 3, 7-dimethyloct-6-en-1-ol showed a comparable activity to standard. Conclusion: The present investigation indicates the probable use of T. capensis extracts in the evaluation of analgesic activity.