Standardization of non-specific parameters of ethanolic extract of mushroom (Ganoderma amboinense)

Abstract

Introduction: The purpose of this research to measure the quality of ethanolic extract of Ganoderma amboinense as source of herbal medicine. The quality parameters of the ethanolic extract of G. amboinense contain non-specific parameters. Materials and Methods: G. amboinense extract is made by maceration method using 96% ethanol to obtain a thick extract. Extracts are tested the moisture content, water content, ash content, acid-insoluble ash content, density, microbial contamination, and metal content. Metal content of lead (Pb) and cadmium (Cd) is determined using atomic absorption spectrophotometer. Results: This research resulted that the parameters of G. amboinense such as water content (7.95 ± 0.49%) v/w, total ash content of powders and extracts of 1.13 ± 0.12% and 2.13 ± 0.26%, acid-insoluble ash content of powders and extracts of 0.68 ± 0.25% and 1.12 ± 0.38%, the density of the extract (0.68 ± 0.25%), and the metal content of Pb extract (0.162 ± 0.01 ppm and Cd is not detection). Conclusion: The conclusion showed that the ethanol extract of G. amboinense has good non-specific parameters and it conducted in accordance to good extract quality requirements.