Phytochemistry and pharmacology of Tecomella undulata
DOI:
https://doi.org/10.22377/ijgp.v8i1.346Abstract
Tecomella undulata (Bignoniaceae) is a monotypic genus and one of the most important deciduous, ornamental shrub or smalltree of the acrid zone of India. Locally known as Rohida, Roheda in Hindi, Rakhtroda in Marathi, Dadimacchada, Chalachhada,
Dadimapuspaka in Sanskrit mostly found in the Thar desert regions of India and Pakistan. The plant holds tremendous potential of medicinal value and is used in traditional and folklore system of medicines. It has been used traditionally in various ailments like syphilis, swelling, leucorrhoea and leucoderma, enlargement of spleen, obesity, tumours, blood disorders, flatulence and abdominal pain. Tecomella undulata has gained prominence due to presence of some prominent secondary metabolites of great therapeutic
potential like stigmasterol, β‑sitosterol, α‑lapachone, tectol isolated from heartwood, bark and leaf. The present review presents the traditional information and recent scientific update on this plant with therapeutic potential.
Key words: Hepatoprotective, pharamacology, phytochemistry, Tecomella undulata
Downloads
References
Ivanova DD, Gerova D, Chervencov T, Yankova T. Polyphenol
and antioxidant capacity of Bulgarian medicinal plants.
J Ethanopharmacol 2005;96:145‑50.
Meena KL, Yadav BL. Studies on ethnomedicinal plants conserved
by Garasia tribes of Sirohi district Rajasthan India. Indian J Nat
Prod Res 2010;1:500‑6.
Chal J, Kumar V, Kaushik S. A Phytopharmacological overview
on Tecomella undulata G. Don. J App Pharm Sci 2011;01:11‑2.
Pandya D, Dhankecha RB, Rathod KD, Dhameliya MB,
Desai TR, Patel VL. Pharmacognostic and Phytochemical
evaluation of leaves of Tecomella undulata. Int J Biol Pharm Res
;3:164‑8.
The Wealth of India; Raw materials. New Delhi: Council of
Scientific and Industrial Research Publications; Vol. 10. 2005.
p. 130‑3.
The Wealth of India. New Delhi: National institute of Science
communication and information resources and Central drug
research Institute Publications; 2008. p. 195‑8.
The Wealth of India. New Delhi: A Dictionary of Indian Raw
Material and Industrial Products‑Raw Material Series. NISCAIR,
CSIR; 1962. p. 195‑6.
Muhammad IC, Khan MA. An Ethanomeditional inventory of
plants used for family planning and sex disease in Samahni valley,
Pakistan. Indian J Trad Know 2008;7:277‑83.
Katewa SS, Galav PK. Traditional herbal medicines from
Shekhawati region of Rajasthan. Indian J Trad Know 2005;4:237‑45.
Pandey VB, Dasgupta B. A new ester glycoside from the bark of
Tecomella undulata. Experentia 1970;26:1187‑8.
Kritikar KR, Basu BD. Indian medicinal plants. In: Blatter E,
Caius JE, Mhaskar KS, editors. Dheradun: Orinental Enterprises
Publication; 2001. p. 2536‑7.
Tareen RB, Bibi T, Khan MA, Ahamd M, Zafar M. Indigenous
knowledge of folk medicine by the women of Kalat and Khuzdr
regions of Balochistan, Pakistan. Pak J Bot 2010;42:1465‑85.
Khare CP. Indian Herbal Remedies, Rational western therapy,
Ayurvedic and other traditional usage. New Delhi: Society of new
age herbals Publication; 2004. p. 67‑9.
Meena AK, Rao MM. Folk herbal medicines used by the Meena
community in Rajasthan. Asian J Trad Med 2005;5:19‑31.
Oudhia P. Medicinal herbs of Chhatisgarh, India having less Known
traditional uses Rohida (Tecomella undulata Family: Bignoniaceae);
Available from: http://botanical.com/site/columnpoudhia/
articles/449rohedahtml [Last accessed on 2012 Sep 10].
Singh P, Khandelwal P, Hara N, Asai T, Fujimoto Y. Radermachol
and napthoquinone derivatives from Tecomella undulata
complete1 H and 13C NMR assignments of Radermachol with aid
of computational 13C shift prediction. Indian J Chem 2008;47B:
‑70.
Gupta SR, Malik KK, Seshadri TR. Lapachol from the heartwood
of Tecomella undulata and a note on its reaction. Indian J Chem
;7:457‑9.
Joshi KC. Quinonoind and other constituents from the heartwood
of Tecomella undulata. Phytochemistry 1974;13:663‑4.
Joshi KC, Sharma AK, Singh P. A new ferulic ester from Tecomella
undulata. Planta Med 1986;1:71‑2.
Hoshi KC, Singh P, Pardasani RT. Quinones and other constituents
from the roots of Tecomella undulata. Planta Med 1977;31:14‑6.
Azam MM, Ghanim A. Tecomella undulata: A Potential of anti‑AIDS
agents. Ann Arid Z 2000;39:93‑6.
Verma KS, Sood GR, Gupta SR, Gujral VK. Structure and
configuration of tecoside, a new irridoid glucoside from Tecomella
undulata. J Chem Soc‑Perki Transac 1979;1:2473‑7.
Gujral VK, Gupta SR, Verma A. New chromone glycoside from
Tecomella undulata. Phytochemistry 1979;18:181‑2.
Taneja SC, Bhatnagar RP, Jiwari HP. Chemical constituents of
flowers of Tecomella undulata. Indian J Chem 1975;13:427‑8.
Joshi KC, Prakash L, Singh LB. 6‑O‑veratryl catalposide: A new
irriod glycoside from Tecomella undulata. Phytochemistry
;14:1441‑2.
Indian Medicinal plants, An illustrated Dictionary. Berlin: CP
Khare, New York: Springer; 2007. p. 649‑51.
Lira AA, Sester EA, Carvalho AL, Strattmann RR, Albuauerque MM,
Wanderley AG, et al. Development of lapachol Topical formulation:
Anti‑inflammatory study of selected formulation. AAPS. Pharm
Sci Tech 2008;9:163‑8.
Hussain H, Krohn K, Ahmad VU, Miana GA, Green IR. Lapachol:
An overview. Arkivoc 2007;2:145‑71.
Choudhury GP. Immunomodulatory activity of alcoholic extract
of Tecoma undulata Linn. in mice. Asian J Biol Res 2011;1:67‑70.
Garkavtsev I, Chauhan VP, Wong HK, Mukhopadhyay A,
Glicksman MK, Peterson RT, et al. Dehydro‑ α‑lapachone, a
plant product with antivascular activity. Proc Natl Acad Sci USA
;108:11596‑601.
Pardee AB, Li YZ, Li CJ. Cancer therapy with beta‑lapachone. Curr
Cancer Drug Targets 2002;2:227‑42.
Renou SG, Asie SE, Abasolo MI, Bekerman DG, Bruno AM.
Monoarylhydrazones of α‑Lapachone: Synthesis, chemical
properties and antineoplastic activity. Pharmazie 2003;58:690‑5.
Bouic PJ, Lamprecht JH. Plant sterols and sterolins: A review
of their immune–modulating properties. Altern Med Rev
;4:170‑7.
Toker G, Turkoz S, Erdemogly N. High performance liquid
chromatographic analysis of rutin in some Turkish Plants II.
J Chem Soc of Pak 1998;20:240‑3.
Erock S, Erkoc F, Keskin N. Theretical investigation of quercetin
and its radical isomers. J Mol Str 2003;631:141‑6.
Formica JV, Regelson W. Review of the biology of quercetin and
related bioflavonoids. Food Chem Toxicol 1995;33:1061‑80.
Di Carlo G, Mascolo N, Izzo AA Capasso F. Flavonoids: Old
and new aspects of a class of natural therapeutic drugs. Life Sci
;65:337‑53.
Harborne JB. Phytochemical methods‑A guide to modern
techniques of plants analysis. 3rd ed. UK: Chapman and Hall;
‑9.
Rao MM, Kingston DG. Plant anticancer agents. XII isolation and
structure elucidation of new cytotoxic quinones from Tabebuia
cassinoids. J Nat Prod 1982;45:600‑4.
Azam MM, Singh P, Ghanim A. Tricontanol and triterpenes from
Tecomella undulata. XI World forestry congress, Antalya, Turkey;
Jain M, Kapadia R, Jadeja RN, Thounaojam MC, Devkar RV,
Mishra SH. Hepatoprotective potential of Tecomella undulata
stem bark is partially due to the presence of betulinic acid.
J Ethanopharmacol 2012;143:194‑200.
Rana MG, Katbamna RV, Duhrejiya AV, Sheth NR. Hepatoprotection
of Tecomella undulata against experimentally induced liver injury
in rats. Pharmacologyonline 2008;3:674‑82.
Khatri A, Garg A, Agarwal SS. Evaluation of hepatoprotective
activity of aerial parts of Tephrosia purpurea Linn. and stem bark
of Tecomella undulata. J Ethanopharmacol 2009;122:1‑5.
Patel KN, Gupta G, Goyal M, Nagpari BP. Assessment of
hepatoprotective effect of Tecomella undulata seem (Bignoneacae) on
paracetamol induced hepatotoxicity in rats. Rev Bras Farmacogn
;21:133‑8.
Singh D, Gupta RS. Hepatoprotective activity of methanol extract
of Tecomella undulata against alcohol and paracetamol induced
hepatotoxicity in rats. Life Sci Med Res 2011;26:1‑8.
Goyal R, Ravishanker B, Shukla VJ, Singh M. Hepatoprotective
activity of rohitaka ghitra against paracetamol induced liver injury
in rats. Pharmacologia 2012;3:227‑32.
Ahmad F, Khan RA, Rashad S. Preliminary screening of methanolic
extracts of Celastrus peniculatus and Tecomella undulata for analgesic
and anti‑inflammatory activities. J Ethanopharmacol 1994;42:193‑8.
Ravi A, Mallika A, Sama V, Begum AS, Khan RS, Reddy BM.
Antiproliferative activity and standardization of Tecomella undulata
bark extract on K562 cells. J Ethanopharmacol 2011;137:1353‑9.
Savjiyani JV, Dave H, Trivedi S, Rachchh MA, Gokani RH.
Evaluation of anticancer activity of polyherbal formulation. Int J
Cancer Res 2012;8:27‑36.
Azam MM. Anti‑HIV agents and other compounds from Tecomella
undulata. Orient J Chem 1999;15:375‑7.
Kumar S, Sharma S, Vasudeva N, Ranga V. In vivo anti‑hyper
glycemic and anti‑oxidant potentials of ethanolic extract from
Tecomella undulata. Diabetol Metab Syndr 2012;4:33.
Parkesh J, Jadeja D, Chanda S. Efficacy of aqueous and methanol
extracts of some medicinal plants for potential antibacterial
activity. Turk J Biol 2005;29:203‑10.
Danya U, Udhayasankar MR, Arumugasamy K, BAluprakash T.
Bioactivity of Tecomella undulata (G.Don) Seem Bignoniaceae on
Human pathogens. South Asian J Biol Sci 2012;2:71‑82.
Suganya S, Senthil RT, Lakshmi BS, Giridev VR. Herbal drug
incorporated antibacterial nanofibrous mat fabricated by
electrospinning: An excellent matrix for wound dressings. J Appl
Poly Sci 2011;121:2893‑9.
Alvala R, Alvala M, Sama V, Dharmarajan S, Variam Ullas J, B MR.
Scientific evidence for traditional claim of anti‑obesity activity of
Tecomella undulata bark. J Ethnopharmacol 2013;148:441‑8.
Ullah MO, Uddin MJ, Hamid K, Kabir S, Rahman MA,
Choudhuri MS. Studies of various biochemical parameters of rat
plasma following chronic administration of “Rohitakarista†An
Ayurvedic formulation. Pak J Biol Sci 2008;11:2036‑9.