Quantification of phytochemicals and in vitro antioxidant potential of various solvent extracts of certain species of Acanthaceae
DOI:
https://doi.org/10.22377/ijgp.v8i1.355Abstract
Background: Scientific evaluation of traditional knowledge is essential to obtain effective drugs for commercial purposes. Thepresent study is guide to the invention of new antioxidant sources from the Acanthaceae members. Aim: Quantification of certain secondary metabolites and in vitro antioxidant activities of alcoholic and aqueous leaf extracts of Nilgirianthus heyneanus and Peristrophe bicalyculata. Materials and Methods: Both the leaf extracts were tested for various phytochemical constituents such as phenols, tannins, condensed tannins, flavonoids, vitamin C and saponin contents. The extracts were further screened for different antioxidant assays such as reducing power, DPPH▪, nitric oxide, metal chelating, ABTS▪+ scavenging activity, lipid peroxidation preventive property and anti‑haemolytic activities. Results: Acetone fractions of Nilgirianthus heyneanus leaf registered significantly high amount of secondary metabolites and also it effectively scavenged the free radicals in a concentration dependent manner than Peristrophe bicalyculata leaf extracts. Results were compared with standard antioxidants such as rutin, quercetin, BHA and BHT.
Conclusions: This study further confirmed the traditional use of N. heyneanus and P. bicalyculata as a natural source of antioxidants and prevents free radical‑induced life‑threatening diseases.
Key words: In vitro antioxidant activity, Nilgirianthus heyneanus, Peristrophe bicalyculata, quantitative estimations
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