Pharmacognostical, physicochemical and high performance thin layer chromatography evaluation of Dhatryadi kwatha

Abstract

Background: Dhatryadi kwatha is mentioned in Ayurvedic classics as a therapeutic formulation to treat Shwitra (Vitiligo). Vitiligo affects 1% of the population worldwide, but management is until unsatisfactory. Dhatryadi kwatha contains Dhatri (Emblica officinalis Gaertn.), Khadira (Acacia catechu Willd.), and Bakuchi (Psoralea corylifolia Linn.). Dhatri and Khadira both have Kushthaghna property. The skin diseases are considered in the umbrella of Kushtha. Bakuchi has also Kushthaghna property. Thus, it is more effective in Vitiligo internally. Materials and Methods: Dhatryadi kwatha powder was evaluated for their pharmacognostic and pharmaceutical analysis. Results: Microscopic characters were found of Amalaki, Khadira, and Bakuchi. Results obtained in pharmaceutical parameters of Dhatryadi kwatha powder like loss on drying 15.19%, ash value 8.48%, alcohol soluble extract 58.6% w/v, etc., are within limit mentioned by Ayurvedic Pharmacopoeia of India. High performance thin layer chromatography profile of Dhatryadi kwatha powder showed similarities in number of spots. Conclusion: From the study, data developed can be espoused for laying down the standards for Dhatryadi kwatha.