Gas chromatography and mass spectroscopy analysis of bioactive components on the leaf extract of Terminalia coriacea: A potential folklore medicinal plant

Authors

  • Jitendra Patel Department of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad, Telangana, India.

DOI:

https://doi.org/10.22377/ijgp.v11i01.886

Abstract

Aim: This study aimed to investigate the bioactive constituents from methanolic extract of Terminalia coriacea leaves using gas chromatography and mass spectroscopy (GC-MS). Materials and Methods: The methanolic extract obtained was subjected to GC-MS for the determination of bioactive volatile compounds. GC-MS analysis was carried out using 6890 GC with 5973 I MSD column. Results and Discussion: The GC-MS analysis of the methanolic extract revealed the presence of 14 bioactive compounds with valuable biological activities. The major chemical constituents are 1H-inden-1-one,2,3-dihydro-3,3,5,6,- tetramethyl; levoglucosan; neophytadiene; phytol; hexadecanoic acid; n-hexadecanoic acid; stigmasterol; β-sitosterol; raffinose; 1,2-benzenedi carboxylic acid; undecanoic acid; (2 propyl-1,3-dioxolan-2-yl) acetic acid; 2,2 dimethyl propane, and octadecatrienoic acid. Conclusion: The presence of various bioactive compounds in T. coriacea proved the pharmaceutical importance. It can be concluded that the plant investigation has opened up a new perspective in pharmaceutical research, and plants can be used for the development of potential, novel antioxidant agents for the treatment of many diseases.

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Published

2017-04-17