Antihyperlipidemic and cardioprotective effects of plant natural products: A review

Abstract

The present review article explains antihyperlipidemic and cardioprotective effects of various plant natural products. These are antioxidants which found in vegetable oils, fruits, seeds, plant leaves, stem, and plant roots. This article emphasizes therapeutic potential of sulfur-containing compounds, anthraquinones, thiosulfinates and ajoenes, tricin, quercetin, Kaikasaponin III and tectorigenin, polyphenols, vitamins and minerals, flavonoid, and phenolics mainly naringenin; aglycone, flavanone (+)-catechin, (−)-epicatechin, and procyanidin B2, quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin, thymol and carvacrol, ceramicine B (limonoid), ginsenoside Rb1 and Rb2, naphthalenic compounds 6-methoxysorigenin and its glycosides, acylates, madecassoside (terpenoids), Miroestrol (phytoestrogen), quercetin rutinoside (rutin), tournefolal, and tournefolic acids A and B. Few other compounds such as thiobarbituric acid, niacin, hederagenin monodesmosides, kalopanaxsaponin A (KPS-A) and sapindoside C, abietane and seco-abietane diterpenes, lycopene, Curcurbitacins A, B, C, D, E, I, J, K, and L, and Colocynthosides A and B were found active. For a healthy life regular intake of plant natural products or herbal diets significantly reduce the cardiovascular risks. Before use, well-designed clinical trials are essentially required to explore real efficacy and safety of these plant products. For management of cardiovascular risks lipid profile is highly needful at an earlier stage. In addition, microlevel biomolecular changes responsible for multiple morbidities affiliated to CVD diseases must be measured to find minor changes at an earlier stage.